HDinHD: Open Source Science for the HD Research Community
The goal of HDinHD is to foster and support a collaborative community united in its drive to accelerate the development of therapeutics that will delay the onset and/or ameliorate the effects of Huntington’s disease. HDinHD seeks to achieve this through:
- Sharing HD-related primary scientific data
- Sharing analyses and computational models built from HD-related scientific data
- Providing browsing and data interrogation tools over both primary and analyzed data that facilitate data exploration and hypothesis generation
- Building a forum for HD researchers to highlight their data, tools, know-how and insight to the community
The HDinHD website – founded as a partnership between CHDI and the Coppola Lab at UCLA – is currently a joint development effort by CHDI, Bridlewood Consulting and Rancho BioSciences. As you will see when you Register for access, HDinHD highlights data and tools provided by the broader community. If you are interested in Contributing Data to HDinHD, suggest links to other HD-related scientific data or websites, or would otherwise like to provide Feedback to us, we encourage you to do so. HDinHD is for the community; please help us tailor and grow HDinHD in a direction that can make a difference to your research, and ultimately, to improve the lives of HD families.
Want to learn more about HDinHD?
| Watch a detailed video overview of HDinHD presented at the 16th Annual HD Therapeutics Conference (April 2021). The video outlines data resources and tools within HDinHD and provides a detailed demonstration of the new HD Explorer tool. |
Read the following publication introducing HDinHD: HDinHD: A Rich Data Portal for Huntington’s Disease Research, J Huntingtons Dis., 10, 405-412
Latest news and publications from around the HD Ecosystem
HDBuzz
- Tagging the Trash: Turnover of Toxic Huntingtin
- Prilenia’s Application for European Approval of Pridopidine Withdrawn
- Intruders in the Brain: What a Pig Model Reveals about Immune Cells in HD
- The Great Care Conundrum: What “Good” Care Looks Like in Huntington’s Disease
- A Second Path: uniQure Plans Regulatory Filing for AMT-130 in the UK
Literature
- Exploring stigma in Huntington's disease: A scoping review of methods and conceptualizations for understanding experiences of gene expansion carriers and at-risk individuals
- Changing care for patients at risk for Huntington's disease in the United States due to the 21st Century Cures Act
- Induced pluripotent stem cells from a transgenic minipig model of Huntington's disease reveal early metabolic changes
- Agmatine interaction with imidazoline receptor inhibits manifestation of depression-like behavior in 3-Nitropropionic acid-induced Huntington's disease-like phenotype in rats
- Huntington s disease - overview
News
- RNA Origami and Nanopores Accurately Size ALS Genes - Neuroscience News
- Turning Huntington's disease awareness into community support
- Team Hope Walk for Huntington's disease set May 30 at Guthrie Green - Tulsa World
- AAN 2026: Using OCT in Pediatric Multiple Sclerosis | NeurologyLive
- Wisconsin requests proposals for new UW-Madison dorm - The Daily Cardinal




