HDinHD: Open Source Science for the HD Research Community
The goal of HDinHD is to foster and support a collaborative community united in its drive to accelerate the development of therapeutics that will delay the onset and/or ameliorate the effects of Huntington’s disease. HDinHD seeks to achieve this through:
- Sharing HD-related primary scientific data
- Sharing analyses and computational models built from HD-related scientific data
- Providing browsing and data interrogation tools over both primary and analyzed data that facilitate data exploration and hypothesis generation
- Building a forum for HD researchers to highlight their data, tools, know-how and insight to the community
The HDinHD website – founded as a partnership between CHDI and the Coppola Lab at UCLA – is currently a joint development effort by CHDI, Bridlewood Consulting and Rancho BioSciences. As you will see when you Register for access, HDinHD highlights data and tools provided by the broader community. If you are interested in Contributing Data to HDinHD, suggest links to other HD-related scientific data or websites, or would otherwise like to provide Feedback to us, we encourage you to do so. HDinHD is for the community; please help us tailor and grow HDinHD in a direction that can make a difference to your research, and ultimately, to improve the lives of HD families.
Want to learn more about HDinHD?
| Watch a detailed video overview of HDinHD presented at the 16th Annual HD Therapeutics Conference (April 2021). The video outlines data resources and tools within HDinHD and provides a detailed demonstration of the new HD Explorer tool. |
Read the following publication introducing HDinHD: HDinHD: A Rich Data Portal for Huntington’s Disease Research, J Huntingtons Dis., 10, 405-412
Latest news and publications from around the HD Ecosystem
HDBuzz
- Keeping an Eye on HD: Can Visual Thinking Skills Help Track Disease Progression?
- August 2026: This month in Huntington’s disease research
- First participant dosed in the PRECISE-HD trial of pridopidine
- Taking A Short Cut: New Routes to Huntingtin-Lowering Therapies
- A shot in the arm for HTT lowering: INSIGHTT trial begins testing SRP-1005
Literature
- Unawareness of motor deficit in Huntington's disease
- L-theanine from Camellia sinensis (L.) attenuates 3-NP-induced Huntington's disease-like alterations by remedying behavioral patterns and modulating neurotransmitters across three distinct brain regions: evidence from in-vivo and in-silico approaches
- Geometric properties of caudate and putamen mark the progression of Huntington's disease
- Network-based stratification of allele-specific expression reveals patient subgroups in Huntington's disease
- Dysfunction of Primary Cilium in Huntington's Disease: How Mutant Huntingtin Disrupts This Cellular Signaling Hub
News
- Rebecca J. Gehres 1963-2026 - Franklin County Free Press
- UniQure's Path Forward Still Includes Controlled Trial For HD Drug | InsideHealthPolicy.com
- Kim Clement's 2027 Prophecy: Is a Two-Year Timeline Unfolding? - Charisma Magazine Online
- uniQure seeks US approval for Huntington's gene therapy after FDA reversal - ET Pharma
- Misfolded proteins slip past cell cleanups and risk causing disease - News-Medical




