HDinHD: Open Source Science for the HD Research Community
The goal of HDinHD is to foster and support a collaborative community united in its drive to accelerate the development of therapeutics that will delay the onset and/or ameliorate the effects of Huntington’s disease. HDinHD seeks to achieve this through:
- Sharing HD-related primary scientific data
- Sharing analyses and computational models built from HD-related scientific data
- Providing browsing and data interrogation tools over both primary and analyzed data that facilitate data exploration and hypothesis generation
- Building a forum for HD researchers to highlight their data, tools, know-how and insight to the community
The HDinHD website – founded as a partnership between CHDI and the Coppola Lab at UCLA – is currently a joint development effort by CHDI, Bridlewood Consulting and Rancho BioSciences. As you will see when you Register for access, HDinHD highlights data and tools provided by the broader community. If you are interested in Contributing Data to HDinHD, suggest links to other HD-related scientific data or websites, or would otherwise like to provide Feedback to us, we encourage you to do so. HDinHD is for the community; please help us tailor and grow HDinHD in a direction that can make a difference to your research, and ultimately, to improve the lives of HD families.
Want to learn more about HDinHD?
| Watch a detailed video overview of HDinHD presented at the 16th Annual HD Therapeutics Conference (April 2021). The video outlines data resources and tools within HDinHD and provides a detailed demonstration of the new HD Explorer tool. |
Read the following publication introducing HDinHD: HDinHD: A Rich Data Portal for Huntington’s Disease Research, J Huntingtons Dis., 10, 405-412
Latest news and publications from around the HD Ecosystem
HDBuzz
- Studying Stutters: What 900,000 genomes teach us about growing DNA repeats
- Highlighting Mental Health Disparities in Indigenous Communities Affected by Huntington’s Disease
- Encouraging news from Skyhawk, as SKY-0515 Phase 1/2 data continues to hold promise
- Food for Thought: The Importance of Nutrition in Huntington’s Disease
- Could Brain Waves Help Track Huntington’s Disease?
Literature
- miR-196a reduces mutant Huntingtin aggregates by Rad23b-mediated degradation in Huntington's disease
- Fluid and Imaging Biomarkers in Huntington's Disease
- Imaging the glymphatic system in Huntington's disease: The benefits of a multimodal approach and clinical implications
- Decreased cerebrospinal fluid TNFRSF8 (sCD30) confirmed as a biomarker of Huntington's disease progression
- Evaluation of curcumin as an exploratory pharmacological tool for modulating dysregulated molecular pathways in cellular models of Huntington's disease
News
- uniQure stock falls 10.38 percent as cash reaches USD 810.3 million - AD HOC NEWS
- Multi-million dollar grants aim to advance hairy cell leukemia research - News-Medical
- Protein modification network plays vital role in cancer development - News-Medical
- Pharmacy Cybersecurity Risks From Phishing and Vishing
- Specialty Pharmacy DEA Inspections - Be Prepared




