HDinHD: Open Source Science for the HD Research Community
The goal of HDinHD is to foster and support a collaborative community united in its drive to accelerate the development of therapeutics that will delay the onset and/or ameliorate the effects of Huntington’s disease. HDinHD seeks to achieve this through:
- Sharing HD-related primary scientific data
- Sharing analyses and computational models built from HD-related scientific data
- Providing browsing and data interrogation tools over both primary and analyzed data that facilitate data exploration and hypothesis generation
- Building a forum for HD researchers to highlight their data, tools, know-how and insight to the community
The HDinHD website – founded as a partnership between CHDI and the Coppola Lab at UCLA – is currently a joint development effort by CHDI, Bridlewood Consulting and Rancho BioSciences. As you will see when you Register for access, HDinHD highlights data and tools provided by the broader community. If you are interested in Contributing Data to HDinHD, suggest links to other HD-related scientific data or websites, or would otherwise like to provide Feedback to us, we encourage you to do so. HDinHD is for the community; please help us tailor and grow HDinHD in a direction that can make a difference to your research, and ultimately, to improve the lives of HD families.
Want to learn more about HDinHD?
| Watch a detailed video overview of HDinHD presented at the 16th Annual HD Therapeutics Conference (April 2021). The video outlines data resources and tools within HDinHD and provides a detailed demonstration of the new HD Explorer tool. |
Read the following publication introducing HDinHD: HDinHD: A Rich Data Portal for Huntington’s Disease Research, J Huntingtons Dis., 10, 405-412
Latest news and publications from around the HD Ecosystem
HDBuzz
- Joining the Starting Lineup: MutLβ’s Role in DNA Repeat Expansions
- Catching a Giant Protein: Five New Ways to Grab Huntingtin
- Mirror, Mirror on the Wall: When Self-Awareness Shifts in Huntington’s Disease
- More Than Just Food: The Hidden Challenges of Eating with Huntington’s Disease
- Roche ends two Huntington’s disease drug programmes after disappointing results
Literature
- USP28 Deficiency is Linked to Impaired Ubiquitin-dependent Proteostasis in Huntington's Disease
- From glycemic control to neuroprotection: alogliptin as a repurposed candidate for Huntington's disease
- Emotion regulation across disease stages in Huntington's disease gene expansion carriers
- The Recommendation Paradox: Perspectives on Genetic Testing in Huntington's Disease Families
- Understanding the cellular architecture of Huntington's disease
News
- Sage Therapeutics Lawsuit: Company Asks Court to Dismiss Investor Securities Claims
- Why Teva Pharmaceutical Stock Is a Buy Despite Trump Tariff Threat - Barron's
- In Vivo CRISPR Therapy is One Step Closer to the Clinic - Bio-IT World
- This Cork sunflower-picking field is back (and it's all for a brave local teenager)
- Abu Dhabi scientists make breakthrough in fight against malaria - The National News




