HDinHD: Open Source Science for the HD Research Community
The goal of HDinHD is to foster and support a collaborative community united in its drive to accelerate the development of therapeutics that will delay the onset and/or ameliorate the effects of Huntington’s disease. HDinHD seeks to achieve this through:
- Sharing HD-related primary scientific data
- Sharing analyses and computational models built from HD-related scientific data
- Providing browsing and data interrogation tools over both primary and analyzed data that facilitate data exploration and hypothesis generation
- Building a forum for HD researchers to highlight their data, tools, know-how and insight to the community
The HDinHD website – founded as a partnership between CHDI and the Coppola Lab at UCLA – is currently a joint development effort by CHDI, Bridlewood Consulting and Rancho BioSciences. As you will see when you Register for access, HDinHD highlights data and tools provided by the broader community. If you are interested in Contributing Data to HDinHD, suggest links to other HD-related scientific data or websites, or would otherwise like to provide Feedback to us, we encourage you to do so. HDinHD is for the community; please help us tailor and grow HDinHD in a direction that can make a difference to your research, and ultimately, to improve the lives of HD families.
Want to learn more about HDinHD?
| Watch a detailed video overview of HDinHD presented at the 16th Annual HD Therapeutics Conference (April 2021). The video outlines data resources and tools within HDinHD and provides a detailed demonstration of the new HD Explorer tool. |
Read the following publication introducing HDinHD: HDinHD: A Rich Data Portal for Huntington’s Disease Research, J Huntingtons Dis., 10, 405-412
Latest news and publications from around the HD Ecosystem
HDBuzz
- Unzipping the Secrets of DNA Repair
- Tooth fairy therapy? Stem cells from teeth tested in a small Huntington’s disease trial
- New insights into intermediate CAG repeats: Mapping the expansion continuum
- UniQure and FDA No Longer in Alignment on Approval Pathway for AMT-130
- October 2025: This Month in Huntington’s Disease Research
Literature
- Huntington's Disease and Psychiatric Comorbidities: A Retrospective Study in Portugal
- Bromelain Alleviates 3-Nitropropionic Acid-Induced Huntington's Disease-Like Symptoms in Rats Through the Interplay of SIRT1/PGC-1alpha and FOXO3a Pathways
- CRISPR-based gene therapy for huntington's disease: current advances and future prospects
- BDNF Mitigates Early Oxidative Stress and Promotes Release of Neuroprotective Mitochondria From Striatal Astrocytes of zQ175 Huntington's Disease Mice
- Brain organoid models of Huntington's disease shift the focus towards neurodevelopment
News
- Family pleads for help to save Spokane father battling rare, excruciating disease - YouTube
- FROM THE LABS: In Memoriam: Bert W. O'Malley, MD - Baylor College of Medicine Blog Network -
- Rod Wilhelm Nominated for Time Dealer of the Year | News Dakota
- Honoring loved ones lost to Huntington's disease
- My experience of a Churchill Fellowship - RCSLT




