HDinHD: Open Source Science for the HD Research Community
The goal of HDinHD is to foster and support a collaborative community united in its drive to accelerate the development of therapeutics that will delay the onset and/or ameliorate the effects of Huntington’s disease. HDinHD seeks to achieve this through:
- Sharing HD-related primary scientific data
- Sharing analyses and computational models built from HD-related scientific data
- Providing browsing and data interrogation tools over both primary and analyzed data that facilitate data exploration and hypothesis generation
- Building a forum for HD researchers to highlight their data, tools, know-how and insight to the community
The HDinHD website – founded as a partnership between CHDI and the Coppola Lab at UCLA – is currently a joint development effort by CHDI, Bridlewood Consulting and Rancho BioSciences. As you will see when you Register for access, HDinHD highlights data and tools provided by the broader community. If you are interested in Contributing Data to HDinHD, suggest links to other HD-related scientific data or websites, or would otherwise like to provide Feedback to us, we encourage you to do so. HDinHD is for the community; please help us tailor and grow HDinHD in a direction that can make a difference to your research, and ultimately, to improve the lives of HD families.
Want to learn more about HDinHD?
| Watch a detailed video overview of HDinHD presented at the 16th Annual HD Therapeutics Conference (April 2021). The video outlines data resources and tools within HDinHD and provides a detailed demonstration of the new HD Explorer tool. |
Read the following publication introducing HDinHD: HDinHD: A Rich Data Portal for Huntington’s Disease Research, J Huntingtons Dis., 10, 405-412
Latest news and publications from around the HD Ecosystem
HDBuzz
- January 2026: This Month in Huntington’s Disease Research
- Phase 1 results announced for Skyhawk’s drug SKY-0515
- Huntington’s Disease Community Advocacy Helps Land Critical FDA Meeting for AMT-130
- Better Sleep, Better Function: New Study Links Sleep Quality to Clinical Outcomes in Huntington’s Disease
- Keeping up with HD research just got easier: Introducing the HDBuzz Trial Tracker
Literature
- Co-Design of a New Integrated Care Model With People Affected by Huntington's Disease: A Mixed Methods Study
- Executive Impairment in Huntington's Disease: Insights From a Systematic Review of the Literature
- Exploring huntington's disease from a neurodevelopmental perspective
- Non-Directiveness and Authenticity in the Predictive Genetic Clinic
- From Cancer to Neuroprotection: Pazopanib Modulates the RIPK1/RIPK3/MLKL and PGAM5/DRP1 Pathways in 3- Nitropropionic Acid-Induced Huntington's Disease
News
- General Hospital Spoilers, February 4: Dark Willow's dirtiest move yet? - Soap Central
- GENERAL HOSPITAL: Britt's Meds are Missing, Willow Blackmails Alexis, Emma Gets a Call ...
- General Hospital Spoilers: THIS Port Charles Couple Welcomes a Blizzard Baby!
- Successful World First: Baby Treated with Personalized CRISPR Gene Therapy for Rare ...
- Turns out inherited eye diseases aren't a sure thing - Harvard Gazette




