HDinHD: Open Source Science for the HD Research Community
The goal of HDinHD is to foster and support a collaborative community united in its drive to accelerate the development of therapeutics that will delay the onset and/or ameliorate the effects of Huntington’s disease. HDinHD seeks to achieve this through:
- Sharing HD-related primary scientific data
- Sharing analyses and computational models built from HD-related scientific data
- Providing browsing and data interrogation tools over both primary and analyzed data that facilitate data exploration and hypothesis generation
- Building a forum for HD researchers to highlight their data, tools, know-how and insight to the community
The HDinHD website – founded as a partnership between CHDI and the Coppola Lab at UCLA – is currently a joint development effort by CHDI, Bridlewood Consulting and Rancho BioSciences. As you will see when you Register for access, HDinHD highlights data and tools provided by the broader community. If you are interested in Contributing Data to HDinHD, suggest links to other HD-related scientific data or websites, or would otherwise like to provide Feedback to us, we encourage you to do so. HDinHD is for the community; please help us tailor and grow HDinHD in a direction that can make a difference to your research, and ultimately, to improve the lives of HD families.
Want to learn more about HDinHD?
| Watch a detailed video overview of HDinHD presented at the 16th Annual HD Therapeutics Conference (April 2021). The video outlines data resources and tools within HDinHD and provides a detailed demonstration of the new HD Explorer tool. |
Read the following publication introducing HDinHD: HDinHD: A Rich Data Portal for Huntington’s Disease Research, J Huntingtons Dis., 10, 405-412
Latest news and publications from around the HD Ecosystem
HDBuzz
- A Window into the Eyes: Using Ocular Biomarkers to Track Progression in Huntington’s Disease
- A Fault In The Supercomputer
- Split Between Two Worlds: The Psychological Challenges for People at Risk of Huntington’s Disease
- Putting it in print: oral drug branaplam lowered huntingtin, but safety concerns halted development
- A hitch in the stitch reveals why DNA sequence patterns matter in Huntington’s disease
Literature
- Electroconvulsive therapy in a patient with Huntington's disease and depression: a case-report
- Ubiquitin ligase Nedd4 regulates the abundance and toxicity of mutant huntingtin
- Differences in white matter detected by ex vivo 9.4 T MRI are associated with axonal changes in the R6/1 model of Huntington's disease
- Decreased Physical Activity as an Early Digital Biomarker in Huntington's Disease: A One-Year Observational Study
- Co-Design of a New Integrated Care Model With People Affected by Huntington's Disease: A Mixed Methods Study
News
- Mavenir Partners With TextNow to Evolve App-Based 5G MVNO Service | Be Korea-savvy
- Neurocrine Biosciences to Present at Upcoming Investor Conferences in March
- Building a Tardive Dyskinesia Center of Excellence: A Multidisciplinary Model
- Combining 2 drugs could slow nerve cell death in Huntington's: Study
- Vico Therapeutics Announces Patient Dosing in Twice-Annual Regimen of VO659 in Phase ...




