HDinHD: Open Source Science for the HD Research Community
The goal of HDinHD is to foster and support a collaborative community united in its drive to accelerate the development of therapeutics that will delay the onset and/or ameliorate the effects of Huntington’s disease. HDinHD seeks to achieve this through:
- Sharing HD-related primary scientific data
- Sharing analyses and computational models built from HD-related scientific data
- Providing browsing and data interrogation tools over both primary and analyzed data that facilitate data exploration and hypothesis generation
- Building a forum for HD researchers to highlight their data, tools, know-how and insight to the community
The HDinHD website – founded as a partnership between CHDI and the Coppola Lab at UCLA – is currently a joint development effort by CHDI, Bridlewood Consulting and Rancho BioSciences. As you will see when you Register for access, HDinHD highlights data and tools provided by the broader community. If you are interested in Contributing Data to HDinHD, suggest links to other HD-related scientific data or websites, or would otherwise like to provide Feedback to us, we encourage you to do so. HDinHD is for the community; please help us tailor and grow HDinHD in a direction that can make a difference to your research, and ultimately, to improve the lives of HD families.
Want to learn more about HDinHD?
| Watch a detailed video overview of HDinHD presented at the 16th Annual HD Therapeutics Conference (April 2021). The video outlines data resources and tools within HDinHD and provides a detailed demonstration of the new HD Explorer tool. |
Read the following publication introducing HDinHD: HDinHD: A Rich Data Portal for Huntington’s Disease Research, J Huntingtons Dis., 10, 405-412
Latest news and publications from around the HD Ecosystem
HDBuzz
- Between Care, Genes, and Systems: Navigating Huntington’s Disease as a Caregiver
- Your Wrist on Watch: Could a Smartwatch Reveal Huntington’s Disease Symptoms?
- March 2026: This Month in Huntington’s Disease Research
- Two Heads Are Better Than One: Combined Physical and Music Therapy for Late-Stage Huntington’s Disease
- A Guest Perspective for Gratitude Day: Why Huntington’s Disease May Be Neuroscience’s Best Investment
Literature
- Profiles of patients at early stages of Huntington's disease based on the routine biological markers and the disease progression
- Inhibition of the NLRP3 Inflammasome With MCC950 Improves Gut Health in Huntington's Disease Mice
- Clozapine-Induced Myocarditis in Huntington's Disease: Case Report
- A small-molecule stabilizer of the calpastatin-calpain-2 complex restores mitochondrial function and mitigates neurodegeneration
- Self-inactivating AAV-CRISPR at different ages enables sustained amelioration of Huntington's disease deficits in BAC226Q mice
News
- Long-term care insurance reduces financial burden for elderly households
- Soleno Therapeutics Shares Surge 56.4% Over the Past Week: The Reasons Explained
- Population-scale repeat expansions elucidate disease risk and brain atrophy - Nature
- Letter: Time matters for Huntington's disease families - Daily Freeman
- GH Spoilers: Britt Shocks Sidwell By Revealing Cullum Stabbed Marco - Soap Opera Spy




