HDinHD: Open Source Science for the HD Research Community
The goal of HDinHD is to foster and support a collaborative community united in its drive to accelerate the development of therapeutics that will delay the onset and/or ameliorate the effects of Huntington’s disease. HDinHD seeks to achieve this through:
- Sharing HD-related primary scientific data
- Sharing analyses and computational models built from HD-related scientific data
- Providing browsing and data interrogation tools over both primary and analyzed data that facilitate data exploration and hypothesis generation
- Building a forum for HD researchers to highlight their data, tools, know-how and insight to the community
The HDinHD website – founded as a partnership between CHDI and the Coppola Lab at UCLA – is currently a joint development effort by CHDI, Bridlewood Consulting and Rancho BioSciences. As you will see when you Register for access, HDinHD highlights data and tools provided by the broader community. If you are interested in Contributing Data to HDinHD, suggest links to other HD-related scientific data or websites, or would otherwise like to provide Feedback to us, we encourage you to do so. HDinHD is for the community; please help us tailor and grow HDinHD in a direction that can make a difference to your research, and ultimately, to improve the lives of HD families.
Want to learn more about HDinHD?
| Watch a detailed video overview of HDinHD presented at the 16th Annual HD Therapeutics Conference (April 2021). The video outlines data resources and tools within HDinHD and provides a detailed demonstration of the new HD Explorer tool. |
Read the following publication introducing HDinHD: HDinHD: A Rich Data Portal for Huntington’s Disease Research, J Huntingtons Dis., 10, 405-412
Latest news and publications from around the HD Ecosystem
HDBuzz
- A Second Path: uniQure Plans Regulatory Filing for AMT-130 in the UK
- Two Years In: New Long-Term Extension Data from PIVOT-HD for Votoplam
- April 2026: This Month in Huntington’s Disease Research
- The Number on the Scale: What the TFC Score Measures, and Why It Matters Right Now
- Dancing With a Stranger: Understanding Apathy in Huntington’s Disease Through Caregivers
Literature
- Huntington s disease - overview
- 'It's more than just irritability': perspectives and experiences of irritability among people affected by Huntington's disease
- MMP9 as a shared immune-related gene in Alzheimer's and Huntington's diseases: a cross-tissue transcriptomic analysis
- Longitudinal trajectories of apathy in Huntington's disease: a 6-year follow-up study
- Relapsing-remitting multiple sclerosis in a patient with Huntington's disease
News
- Declare Huntington's as rare disease: Experts - The New Indian Express
- Rebukes of Trump's Pick for FDA Head Miss One Critical Fact - The Western Journal
- Declare Huntington's as rare disease: Experts | The Morning Standard - newspaper - Magzter
- Latus Bio to Present Gene Therapy Data at ASGCT - MyChesCo
- FDA Policies: Rigorous Science or Roadblocks? - WSJ




